Thursday, September 11, 2008

Deadly Delay,Why are minorities with cancer getting diagnosed late? (Newsweek)

On a hot summer day in 2006, an African-American woman walked into the emergency room at Grady Memorial Hospital in Atlanta complaining of a large sore on her breast. Her family had urged her to go to the hospital, she said, because the stench from the infected wound had become intolerable. Doctors discovered a cancerous tumor so large it had burst through her skin.

When Otis Brawley, then medical director of the hospital's cancer center, asked the woman when she had first noticed a lump in her breast, she recalled that her son had been in second grade. He was now a high school junior. Even after the tumor first broke through her skin, she admitted waiting nearly two more years to seek treatment. She had no health insurance, she explained. Apparently she hadn't realized that, as a public hospital, Grady accepts and treats the uninsured. Despite the intense treatment that followed—a mastectomy, along with radiation and chemotherapy—her cancer was already so advanced that she was dead within a year.

Her case might seem extreme, but Brawley says at Grady's cancer center, where the majority of patients are minorities and many are uninsured, "that sort of thing happens several times a year." When he examined hospital records, he found that, on average, about 40 percent of the breast cancer patients treated there have already reached stage IV, for which the five-year survival rate is just 20 percent (versus nearly 100 percent for those diagnosed at stage 1). By comparison, only a small percentage of the patients he saw at Emory University's cancer institute, which serves a largely white, middle-class population, had progressed to a late stage when they were diagnosed.

The situation at Atlanta's public hospital is hardly unique. In a new study, which will be published in the March issue of the journal Lancet Oncology, researchers at the American Cancer Society (ACS)—where Brawley is now chief medical officer—analyzed records of more than 3.7 million cancer patients diagnosed between 1998 and 2004 throughout the country. They found that minority and uninsured cancer patients like the woman at Grady Memorial Hospital have a significantly higher risk than white patients and those with private insurance of having reached an advanced stage of the disease by the time they are diagnosed or seek treatment. That means they are more likely to endure excruciating, and often more expensive, treatments and they are more likely to die from the cancer.

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